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 Formulary Chapter 2: Cardiovascular system - Full Chapter
02.08.02  Expand sub section  Oral anticoagulants
EdoxabanBlack Triangle (Lixiana)
(tablet)
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First Choice
Green

note Due to cost effectiveness this is the first choice DOAC locally for prevention of stroke and systemic embolism in adult patients with nonvalvular atrial fibrillation (NVAF). See DPC Anticoagulant Decision Aid.

Note: other DOACs may be used if considered more clinically appropriate.

 
Apixaban (Eliquis)(AF/VTE)
(tablet)
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Formulary
Green
 
Link  NICE TA275: Apixaban for preventing stroke and systemic embolism in people with nonvalvular AF
Link  NICE TA341: Apixaban for the treatment and secondary prevention of deep vein thrombosis and/or pulmonary embolism
   
Apixaban (Eliquis)(Orthopaedic prophylaxis)
(tablet)
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Formulary
Red
 
Link  NICE TA245: Apixaban for the prevention of VTE after total hip or knee replacement in adults
   
Dabigatran (Pradaxa) (AF/VTE)
(capsule)
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Formulary
Green
 
Link  NICE TA249: Dabigatran for the prevention of stroke and systemic embolism in AF
Link  NICE TA327: Dabigatran etexilate for the treatment and secondary prevention of deep vein thrombosis and/or pulmonary embolism
   
Dabigatran (Pradaxa) (Orthopaedic prophylaxis)
(capsule)
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Formulary
Red
 
Link  NICE TA157: Dabigatran for the prevention of VTE after hip or knee replacement surgery in adults
   
Phenindione
(tablet)
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Formulary
Amber Recommended
 
   
Rivaroxaban (Xarelto) (ACS)
(tablet)
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Formulary
Amber Initiation
 
Link  NICE TA335: Rivaroxaban for preventing adverse outcomes after acute management of ACS
   
Rivaroxaban (Xarelto) (AF/VTE)
(tab)
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Formulary
Green
 
Link  NICE TA256: Rivaroxaban for the prevention of stroke and systemic embolism in people with AF
Link  NICE TA261: Rivaroxaban for the treatment of DVT and prevention of recurrent DVT and PE
Link  NICE TA287: Rivaroxaban for treating PE and preventing recurrent VTE
Link  NICE TA607: Rivaroxaban for preventing atherothrombotic events in people with coronary or peripheral artery disease
Link  Pharmacist checklist for counselling patients starting rivaroxaban for NVAF
   
Rivaroxaban (Xarelto) (Orthopaedic prophylaxis)
(tablet)
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Formulary
Red

  • red for trauma (off-label use)
  • red for off-label use for patients with fractured neck of femur or who have a plaster cast and who fulfil the assessment criteria
 
Link  NICE TA170: Rivaroxaban for the prevention of VTE after total hip or total knee replacement in adults
   
Warfarin
(tablet)
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Formulary
Green
 
   
02.08.02  Expand sub section  Stroke prevention in AF
02.08.02  Expand sub section  VTE treatment
 ....
 Non Formulary Items
Acenocoumarol  (Sinthrome)
(tablets)

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine

Traffic Light Status Information

Status Description

Green

Suitable for prescribing by all in both primary and secondary care.  

Amber Recommended

Specialist recommended but suitable for continuation in primary care.  

Amber Initiation

Specialist initiated but suitable for continuation in primary care.  

Amber SCG

Specialist initiated and for continuation in primary care under a locally approved shared care guideline.  

Red

Suitable for prescribing in specialist settings (secondary care) only.   

Red Specialist Centre

Secondary care medicines to be used under specialised commissioning arrangements only.  

Blue

For primary care, either via FP10 or supplied through specialist services. These products may be stocked by hospital pharmacies only for supply to primary care units/wards or for continuing supplies for patients admitted on therapy.  

Black

Not recommended for use.  

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