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 Formulary Chapter 2: Cardiovascular system - Full Chapter
02.12  Expand sub section  Lipid-regulating drugs
Alirocumab (Praluent)
(injection)
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Formulary
Red
 
Link  NICE TA393: Alirocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia
   
Evolocumab (Repatha )
(injection)
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Formulary
Red
High Cost Medicine
 
Link  NICE TA394: Evolocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia
   
Lomitapide (Lojuxta▼)
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Formulary
Red
High Cost Medicine

Restricted Item In line with commissioning criteria

 
Link  Clinical Commissioning Policy: Lomitapide for treating homozygous familial hypercholesterolaemia (adults)
   
02.12  Expand sub section  Bile acid sequestrants
Colestyramine powder
(sachet)
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Formulary
Amber Recommended
 
   
02.12  Expand sub section  Ezetimibe
Ezetimibe (Ezetrol)
(tablet)
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Formulary
Green

Mainly reserved as an adjunct to statins for patients with primary hypercholesterolaemia.

 
Link  NICE TA385: Ezetimibe for treating primary heterozygous-familial and non-familial hypercholesterolaemia
   
02.12  Expand sub section  Fibrates
Fenofibrate
(capsule)
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First Choice
Green

First choice fibrate.

Consider only when a statin or other treatments are contraindicated or not tolerated.

 
Bezafibrate
(MR tablet)
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Formulary
Amber Recommended

Consider only when a statin or other treatments are contra-indicated or not tolerated

unlicensed Also approved for off-label use for the treatment of primary biliary cholangitis

 
   
02.12  Expand sub section  Statins to top
Atorvastatin
(tablet)
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First Choice
Green
 
Pravastatin
(tablet)
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Formulary
Green
 
   
Rosuvastatin
(tablet)
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Formulary
Green

Restricted Item Reserved for use in patients requiring high intensity statin unable to tolerate/unsuitable for atorvastatin or high dose simvastatin

 
   
Simvastatin
(tablet)
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Formulary
Green
 
   
02.12  Expand sub section  Omega-3 fatty acid compounds
 ....
 Non Formulary Items
Ciprofibrate
(tablets)

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Non Formulary
 
Colestipol  (Colestid)
(sachet)

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Non Formulary
 
Fluvastatin
(capsules/prolonged-release tablets)

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Non Formulary
 
Gemifibrozil
(tablets/capsules)

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Non Formulary
 
Omega 3 fatty acid compounds

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Non Formulary
Black

Self Care Self Care Medicine

NHS England recommendation: Should not be routinely prescribed by CCGs

Link  EMA confirms omega-3 fatty acids not effective in preventing further heart problems after heart attack
 
Simvastatin & ezetimibe  (Inegy)
(tablets)

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine

Traffic Light Status Information

Status Description

Green

Suitable for prescribing by all in both primary and secondary care.  

Amber Recommended

Specialist recommended but suitable for continuation in primary care.  

Amber Initiation

Specialist initiated but suitable for continuation in primary care.  

Amber SCG

Specialist initiated and for continuation in primary care under a locally approved shared care guideline.  

Red

Suitable for prescribing in specialist settings (secondary care) only.   

Red Specialist Centre

Secondary care medicines to be used under specialised commissioning arrangements only.  

Blue

For primary care, either via FP10 or supplied through specialist services. These products may be stocked by hospital pharmacies only for supply to primary care units/wards or for continuing supplies for patients admitted on therapy.  

Black

Not recommended for use.  

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