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 Formulary Chapter 4: Central nervous system - Full Chapter
04.01  Hypnotics and anxiolytics
04.01.01  Hypnotics
04.01.01  Benzodiazepines
Nitrazepam
(tablets/suspension)
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Red
 
   
Controlled Drug Temazepam
(tablet/liquid)
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Formulary
Green
 
   
04.01.01  Zaleplon, Zolpidem and Zopiclone
Zopiclone
(tablet)
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Formulary
Green
 
Link  NICE TA77: Guidance on the use of zaleplon, zolpidem and zopiclone for the short-term management of insomnia
   
04.01.01  Chloral and derivatives to top
Chloral Hydrate 500mg in 5mL
(Elixir)
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Formulary
Red

unlicensed unlicensed

 
   
Chloral Hydrate Suppositories
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Formulary
Red

unlicensed unlicensed

 
   
04.01.01  Clomethiazole (Chlormethiazole)
Clomethiazole (Heminevrin®)
(capsules)
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Formulary
Red
 
   
04.01.01  Melatonin
Melatonin  (Circadin®/ Slenyto®)
(MR tablet)
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Formulary
Amber SCG

Restricted Item CAMHS initiation/supervision only for use in children with sleep disorders in accordance with DPC Shared Care guidance.

Tablets may be crushed but this will result in loss of modified-release properties.

unlicensed Note: use of Circadin in this setting will be off label, but is established practice. Current patients established on this formulation may continue.

 

 

 
   
Melatonin 3mg
(tablets)
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Formulary
Amber SCG

Restricted Item CAMHS initiation/supervision only for use in children with sleep disorders in accordance with DPC Shared Care guidance

unlicensed Note: use in this setting will be off label, but is established practice. Current patients established on this formulation may continue.

May be crushed/ given via PEG if necessary.

 
   
Melatonin 5mg in 5ml
(oral solution)
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Formulary
Amber SCG

Restricted Item CAMHS initiation/supervision only for use in children with sleep disorders in accordance with DPC Shared Care guidance

unlicensed Unlicensed special (e.g. Kidmel®, Neomel®)

Only if licensed products are not suitable.

Consider excipients (e.g. sugar, colours, alcohol, sorbitol, propylene glycol) when prescribing for children.

Note: Melatonin 1mg/ml oral solution (Colonis Pharma Ltd) is unlicensed in children aged 0-18 years, and not recommended due to potentially unsafe excipients. This product is therefore non-formulary.

 

 
   
04.01.02  Anxiolytics
04.01.02  Benzodiazepines
Diazepam
(tablet/liquid/rectal liquid/solution/emulsion injection)
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Formulary
Green
 
   
Lorazepam
(tablet)
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Formulary
Green
 
   
Lorazepam
(injection)
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Formulary
Red
 
   
Clonazepam
(tablet)
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Formulary
Amber Initiation

Restricted Item Southern Health only

 
   
04.01.02  Buspirone to top
Buspirone Hydrochloride
(tablet)
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Formulary
Amber Recommended
 
   
04.01.03  Barbiturates
04.02  Drugs used in psychoses and related disorders
04.02.01  Antipsychotic Drugs
04.02.01  First-Generation Antipsychotic Drugs
Benperidol (Anquil®)
(tablet)
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Formulary
Red

Restricted Item Southern Health use only

 
   
Chlorpromazine
(tablet/liquid)
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Formulary
Green
 
   
Flupentixol
(tablet)
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Formulary
Green
 
   
Haloperidol
(tablet/liquid/injection)
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Formulary
Green
 
   
Levomepromazine
(tablet/injection)
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Formulary
Green
 
   
Promazine Hydrochloride
(tablet/liquid/injection)
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Formulary
Green

Injection is unlicensed unlicensed 

 
   
Sulpiride
(tablet)
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Formulary
Green
 
   
Sulpiride
(liquid)
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Formulary
Red
 
   
Trifluoperazine
(tablet/liquid)
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Formulary
Green
 
   
Zuclopenthixol acetate (Clopixol Acuphase®)
(injection)
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Formulary
Green
 
   
04.02.01  Second-Generation Antipsychotic Drugs to top
Amisulpride
(tablet/liquid)
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Formulary
Green
 
   
Aripiprazole
(tablet)
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Formulary
Amber Recommended
 
Link  NICE TA213: Aripiprazole for the treatment of schizophrenia in people aged 15 -17 years
Link  NICE TA292: Bipolar disorder (children) - aripiprazole
   
Aripiprazole 7.5mg/ml (Abilify®)
(injection (intramuscular))
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Formulary
Red

Restricted Item Specialist use only by Southern Health in accordance with rapid tranquilisation guidelines.

 
   
Clozapine
(tablet)
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Formulary
Red

Restricted Item Specialist use only for treatment resistant schizophrenia

 
   
Olanzapine
(tablet/orodispersible tablet)
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Formulary
Green

Orodispersible tablets restricted to patients with swallowing difficulties

 
   
Quetiapine
(tablet)
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Formulary
Green
 
   
Risperidone
(tablet/liquid/orodispersible tablet)
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Formulary
Green

Orodispersible tablets restricted to patients with swallowing difficulties

 
   
04.02.02  Antipsychotic depot injections
Aripiprazole (Abilify Maintena®)
(depot injection)
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Formulary
Red

Restricted Item Secondary psychiatric care only

note For intramuscular injection

 
   
Flupentixol decanoate
(depot injection)
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Formulary
Amber Initiation

note For deep intramuscular injection

 
   
Fluphenazine decanoate (Modecate®)
(depot injection)
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Formulary
Amber Initiation

note For deep intramuscular injection

 Product has been discontinued in UK, supplies expire in Aug 2020

 
   
Haloperidol decanoate (HALDOL® Decanoate)
(depot injection)
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Formulary
Amber Initiation

note For deep intramuscular injection

 
   
Paliperidone palmitate (Xeplion / Trevicta®)
(depot injection)
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Formulary
Red

Restricted Item  Specialist use at Southern Health/Solent NHS Trust

note For intramuscular injection. Xeplion = 1-monthly, Trevicta = 3-monthly maintenance dosing.

 
   
Pipotiazine palmitate (Piportil® Depot)
(depot injection)
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Formulary
Amber Initiation

Restricted Item  Southern Health only

note For deep intramuscular injection

 
   
Risperidone (Risperdal Consta®)
(depot injection)
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Formulary
Red

Restricted Item  Psychiatry only

note For deep intramuscular injection

 
   
Zuclopenthixol decanoate (Clopixol®)
(depot injection)
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Formulary
Amber Initiation

note For deep intramuscular injection

 
   
04.02.03  Drugs used for mania and hypomania
04.02.03  Valproic acid
Sodium valproateBlack Triangle
(tablet/MR tablet/liquid)
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Formulary
Green

unlicensed Agreed locally for ‘off-label’ use in treatment of manic episodes in bipolar disorder instead of valproate semisodium.

Brand prescribing is not necessary for this indication.

 

 

 

 
Link  MHRA Drug Safety Update May 2018: Valproate medicines: Pregnancy Prevention Programme materials online
   
04.02.03  Lithium
Lithium Carbonate
(MR tablet)
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Formulary
Amber Initiation

SPECIFY BRAND

 
   
Lithium Citrate
(liquid)
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Formulary
Amber Initiation

Not dose-equivalent to MR tablets

SPECIFY BRAND

 
   
04.03  Antidepressant drugs to top
04.03.01  Tricyclic and related antidepressant drugs
04.03.01  Tricyclic antidepressants
Amitriptyline
(tablet/liquid)
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First Choice
Green

May also be used off-label for hypersalivation

 
Imipramine
(tablet)
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Second Choice
Amber Recommended

note May be considered as a potential second line alternative when amitriptyline is not suitable/not tolerated

 
   
Clomipramine
(capsule)
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Formulary
Amber Recommended
 
   
Lofepramine
(tablet/liquid)
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Formulary
Amber Recommended
 
   
04.03.01  Related antidepressants
Trazodone
(capsule/liquid)
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Formulary
Amber Recommended

For agitation in older people with dementia

 
   
04.03.02  Monoamine-oxidase inhibitors
Phenelzine (Nardil®)
(tablet)
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Formulary
Amber Initiation

Restricted Item Specialist use only

 
   
04.03.03  Selective serotonin re-uptake inhibitors to top
Citalopram
(tablet/oral drops)
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First Choice
Green

Tablets and oral drops are not dose-equivalent

 
Fluoxetine
(capsule/oral solution)
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First Choice
Green

note consider oral solution as a more cost effective alternative to 10mg capsules

 
Sertraline
(tablet)
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First Choice
Green
 
Escitalopram
(tablet)
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Alternatives
Amber Recommended

Third line on specialist advice

Oral drops (Cipralex®) are Non Formulary

 
Link  MHRA Drug Safety Update: Citalopram and escitalopram: QT interval prolongation
   
Paroxetine
(tablet/liquid)
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Alternatives
Amber Recommended
 
   
04.03.04  Other antidepressant drugs
Agomelatine
(tablet)
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Formulary
Amber Recommended

Restricted Item  For use within Southern Health. Initiated or recommended by a psychiatrist.

A third line option where adverse effects of alternative antidepressants make them unacceptable to patients (sexual dysfunction and sleep disturbance)

 
   
Flupentixol
(tablet)
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Formulary
Green
 
   
Mirtazapine
(tablet/orodispersible tablet)
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Formulary
Green

Orodispersible tabs restricted to patients with swallowing difficulties

 
   
Reboxetine
(tablet)
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Formulary
Amber Recommended
 
   
Venlafaxine
(tablet/MR capsule/Mr tablet)
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Formulary
Green

A third line antidepressant

 
   
Venlafaxine XL 225mg
(high dose tablet/high dose capsule)
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Formulary
Amber Recommended

A third line antidepressant

 
   
Vortioxetine
(tablet)
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Formulary
Amber Recommended

Not a first line antidepressant.

 
Link  NICE TA367 - Vortioxetine for treating major depressive episodes
   
04.04  CNS stimulants and other drugs used for attention deficit hyperactivity disorder
 note 

Drugs for ADHD should only be initiated by specialists, but can be continued by GPs

Atomoxetine (Strattera®)
(capsule)
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Formulary
Amber Initiation
 
   
Controlled Drug Dexamfetamine
(tablet)
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Formulary
Amber Initiation
 
   
Guanfacine (Intuniv®)
(Prolonged release tablets)
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Formulary
Amber Initiation

Specialist initiation only

As per DPC Shared Care Guidelines (pending publication)

 
   
Controlled Drug Lisdexamfetamine (Elvanse®)
(capsule)
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Formulary
Amber Initiation

For use according to licence.

 
   
Controlled Drug Methylphenidate
(tablet/MR tablet/MR capsule)
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Formulary
Amber Initiation
 
   
04.04  Narcolepsy medicines
Modafinil
(tablets)
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Formulary
Amber Initiation

Restricted Item Restricted use. For treatment of excessive sleepiness associated with narcolepsy only. Prescribing to be initiated by sleep specialist/neurologist.

Caution: prescribers should be aware of abuse risk (Modafinil: Be Smart) when considering quantities on prescriptions.

Modafinil is not supported for use (off-label) in any other indications in accordance with MHRA safety alert 2011.

 

 
Link  European Medicines Agency review of safety and effectiveness of modafinil Nov 2010
Link  MHRA Safety Update Mar 2011: Modafinil now restricted to narcolepsy
Link  PrescQIPP Bulletin 250: Modafinil Oct 2019
   
Pitolisant (Wakix®)
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Formulary
Red
High Cost Medicine

Restricted Item Restricted use. For specialist sleep clinic use for treatment of narcolepsy in patients aged ≥18 years, only when conventional stimulants have failed/not tolerated, and sodium oxybate is not suitable/not tolerated as per DPC recommendations.

 
   
Controlled Drug Sodium Oxybate (Xyrem®)
(liquid)
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Formulary
Red Specialist Centre
High Cost Medicine

Restricted Item As per NHS England clinical commissioning criteria for use in children (≤18 years).

Adult use (≥19 years) requires IFR submission to CCG.

 
Link  NHS England Clinical Commissioning Policy: Sodium oxybate for symptom control of narcolepsy with cataplexy (children) Dec 2016
Link  RMOC: Sodium oxybate in adult patients Oct 2019
   
04.05  Drugs used in the treatment of obesity
04.05.01  Anti-obesity drugs acting on the gastro-intestinal tract to top
Orlistat
(capsule)
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Formulary
Blue
 
   
04.05.02  Centrally acting appetite suppressants
04.06  Drugs used in nausea and vertigo
04.06  Antihistamines
Cinnarizine
(tablet)
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Formulary
Green

For labyrinthine vertigo or acute treatment of Ménière’s disease

 
   
Cyclizine
(tablet / injection)
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Formulary

Green For oral, intramuscular or subcutaneous administration. Note: subcutaneous administration is off label but is established practice in palliative care. 

Red For intravenous administration. Restricted Item Due to safety concerns, intravenous use of cyclizine at UHS is restricted to short-term (i.e. single dose) only.

 
   
Promethazine
(tablet/liquid)
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Formulary
Green

 

  • 10mg, 25mg tablets
  • 5mg/5ml elixir
 
   
04.06  Phenothiazines and related drugs
Prochlorperazine
(tablet/liquid/injection/buccal tablet)
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Formulary
Green

Buccal tabs are an alternative to injectable antiemetics.

 
   
Levomepromazine
(tablet/injection)
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Formulary
Amber Initiation

Palliative care

 
   
04.06  Domperidone and metoclopramide to top
Domperidone
(tablet/liquid/suppositories)
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Formulary
Green

unlicensed unlicensed suppositories. Also used off-label for stimulation of lactation (contra-indicated in patients with known cardiac problems).

Short-term use only. No longer indicated as a motility stimulant.

 
Link  Domperidone for nausea and vomiting: lack of efficacy in children; reminder of contraindications in adults and adolescents
Link  MHRA Drug Safety Update May 2014: domperidone risk of cardiac side effects
   
Metoclopramide
(tablet/liquid/injection)
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Formulary
Green

Short term use only. No longer indicated as a motility stimulant

 
Link  MHRA Drug Safety Update Aug 2013: metoclopramide risk of neurological adverse effects
   
04.06  5HT3 antagonists
Ondansetron
(tablet/liquid/injection)
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First Choice
Green
 
Granisetron
(tablet/injection)
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Formulary
Amber Recommended

After ondansetron has failed in children receiving chemotherapy and patients with gastrointestinal failure

 
   
Granisetron (Sancuso® )
(patch)
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Formulary
Red

Restricted Item Specialist use only as per licensed indications

 
   
Netupitant and Palonosetron (Akynzeo®)
(capsule)
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Formulary
Red

For prevention of chemotherapy-induced nausea/vomiting

 
   
04.06  Neurokinin receptor antagonist
Aprepitant (Emend®)
(capsule/liquid)
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Formulary
Red

For chemotherapy-induced nausea/vomiting

Liquid for chemotherapy-induced nausea/vomiting in children 6months - 12years

 
   
04.06  Hyoscine
Hyoscine hydrobromide
(tablets/patch/injection)
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Formulary
Amber Recommended

Tablets/patch may also be used off-label for hypersalivation

 
   
04.06  Other drugs for Ménière's disease
Betahistine Dihydrochloride
(tablets)
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Formulary
Green

For prophylaxis in proven Ménière’s disease

 
   
04.07  Analgesics to top
 note 

See section 10.1.1 for non-steroidal anti-inflammatory drugs (NSAIDs)

04.07.01  Non-opioid analgesics and compound analgesic preparations
Aspirin
(tablet/suppositories)
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Formulary
Green

EC tablets are not formulary

 
   
Paracetamol
(tablet/soluble tablet/liquid/suppositories)
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Formulary
Green
 
   
Paracetamol
(injection)
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Formulary
Red

Injection only if oral/rectal routes are unavailable or inappropriate

 
   
04.07.01  Compound analgesic preparations
Paracetamol and codeine (Co-codamol 8/500)
(Effervescent tablet)
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Formulary
Green

Soluble preparations have a high sodium content

 
   
Paracetamol and codeine (Co-codamol 30/500)
(tablet/effervescent tablet)
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Formulary
Green

Restricted Item Effervescent tablets restricted to patients with swallowing difficulties/enteral feeding tubes.

 
   
Paracetamol and dihydrocodeine (Co-dydramol 10/500)
(tablet)
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Formulary
Green
 
Link  MHRA Drug Safety Update Jan 2018: Co-dydramol: prescribe and dispense by strength to minimise risk of medication error
   
04.07.02  Opioid analgesics
Controlled Drug Alfentanil
(injection)
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Formulary
Red
 
   
Controlled Drug Buprenorphine 5-20microgram/hour weekly patch
(patch)
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Formulary
Green

Prescribe by brand name

 
   
Controlled Drug Buprenorphine 35-70microgram/hour 96hour patch
(patch)
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Formulary
Green

Prescribe by brand name

 
   
Codeine Phosphate
(tablet/liquid/suppositories/injection)
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Formulary
Green

unlicensed unlicensed suppositories

 
Controlled Drug Injection Only
   
Controlled Drug Diamorphine
(nasal spray)
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Formulary
Red

Restricted Item Paediatrics

 
   
Controlled Drug Diamorphine
(tablet/injection)
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Formulary
Green
 
   
Dihydrocodeine
(tablet/liquid/MR tablet)
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Formulary
Green
 
   
Controlled Drug Fentanyl
(patch)
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Formulary
Green

Not first line opioid choice

 
   
Controlled Drug Fentanyl (Actiq®)
(lozenge)
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Formulary
Red

Restricted Item  Adult Acute Pain Team only

For painful procedures

Fentanyl lozenge with oromucosal applicator

 
   
Controlled Drug Fentanyl Nasal Spray (PecFent®)
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Formulary
Amber Initiation

Restricted Item For cancer care/palliative care specialist initiation only.

Prescribe by brand name.

For the management of breakthrough pain in adult patients using opioid therapy for chronic cancer pain. Only for patients unable to tolerate, or unsuitable for treatment with, oral formulations of other opioids (e.g. morphine, oxycodone).

 

 
   
Controlled Drug Fentanyl sublingual tablets (Abstral®)
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Formulary
Amber Initiation

Restricted Item For cancer care/palliative care specialist initiation only.

Prescribe by brand name.

For the management of breakthrough pain in adult patients using opioid therapy for chronic cancer pain. Only for patients unable to tolerate, or unsuitable for treatment with, oral formulations of other opioids (e.g. morphine, oxycodone).

 
   
Controlled Drug Methadone 10mg/ml
(liquid)
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Formulary
Red

Restricted Item Palliative Care only

 
   
Controlled Drug Morphine sulphate
(tablet/MR capsule/liquid/MR sachet/injection/suppositories)
View adult BNF View SPC online View childrens BNF
Formulary
Green

Zomorph MR cap is first line oral morphine MR product.

unlicensed unlicensed suppositories

 
   
Controlled Drug Oxycodone
(injection)
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Formulary
Amber Recommended

Restricted Item Amber for use in palliative care in the community, otherwise acute pain team only

Second line PCA

 
   
Controlled Drug Oxycodone
(liquid/capsule/MR tablet)
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Formulary
Green

In UHS, capsules and liquid are GREEN for patients who have previously been prescribed oxycodone MR due to intolerance to morphine

Capsules only for patients unable to tolerate liquid, not for ward stock

Restricted Item Liquid is RED in UHS for patients who require oral treatment after oxycodone PCA. Acute Pain Team recommendation only 

 
   
Controlled Drug Pethidine
(tablet)
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Formulary
Green
 
   
Controlled Drug Pethidine
(injection)
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Formulary
Red
 
   
Controlled Drug Tapentadol
(MR tablet/liquid)
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Formulary
Amber Recommended

Restricted Item Specialist recommendation for third or fourth line use

Liquid for breakthrough pain for patients taking MR tablets only

 
   
Controlled Drug Tramadol
(capsule/MR capsule/MR tablet)
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Formulary
Green

Not a first line option

 
   
Controlled Drug Tramadol
(injection)
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Formulary
Red

Inj only for patients who are NBM

 
   
04.07.03  Neuropathic pain
Paracetamol
(tablet/soluble tablet/liquid/suppositories)
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First Choice
Green

First line for neuropathic pain

 
Amitriptyline
(tablet/liquid)
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Formulary
Green

For neuropathic pain in accordance with NICE Guidelines

unlicensed Off-label use

 
   
Carbamazepine
(tablet/liquid/suppositories)
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Formulary
Green
 
   
Duloxetine
(capsule)
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Formulary
Amber Recommended

For neuropathic pain in accordance with NICE Guidelines

 
   
Controlled Drug Gabapentin
(capsule)
View adult BNF View SPC online View childrens BNF
Formulary
Green

For neuropathic pain in accordance with NICE Guidelines

First line if pain is lancinating in nature (‘electric shocks’)

 
   
Lidocaine
(medicated plaster 5%)
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Restricted Drug Restricted

Restricted Item Restricted use.

Green for use in patients who have been treated in line with NICE CG173: Neuropathic pain, but are still experiencing pain associated with previous herpes zoster infection (post-herpetic neuralgia) (licensed indication).

Amber Initiation Amber for chronic neuropathic pain/focal neuralgia [unlicensed 'off label' use] in exceptional circumstances only (e.g. other treatment options have failed or cannot be used due to co-morbidities) in a co-operation arrangement with chronic pain or cancer care/palliative care specialist teams as per DPC Chronic Pain Prescribing Guidelines or Wessex Palliative Care Guidelines.

Red for use in rib fracture pain (see section 15.02)

 
   
Controlled Drug Pregabalin
(capsule)
View adult BNF View SPC online View childrens BNF
Formulary
Green

For neuropathic pain in accordance with NICE Guidelines

Also amber for epilepsy and green for generalised anxiety disorder (see section 4.8.1)

 
   
Phenytoin
(capsule/liquid)
View adult BNF View SPC online View childrens BNF
Formulary
Green

For trigeminal neuralgia if carbamazepine is ineffective or not tolerated

 
   
04.07.04  Antimigraine drugs to top
04.07.04.01  Treatment of the acute migraine attack
04.07.04.01  Analgesics
 note 

First line option -  Paracetamol or aspirin (preferably in a soluble or dispersible form) +/- metoclopramide

Aspirin
(tablet/soluble tablet/suppositories)
View adult BNF View SPC online View childrens BNF
Formulary
Green

Soluble or dispersible form preferred +/- metoclopramide

 
   
Paracetamol
(tablet/soluble tablet/liquid/suppositories)
View adult BNF View SPC online View childrens BNF
Formulary
Green

Soluble or dispersible form preferred +/- metoclopramide

 
   
04.07.04.01  5HT1 agonists
Sumatriptan
(tablet/injection/nasal spray)
View adult BNF View SPC online View childrens BNF
First Choice
Green

50mg tablet - first line oral triptan

Injection for migraine, if oral or nasal preparations fail, or cluster headache

 
Almotriptan
(tablet)
View adult BNF View SPC online View childrens BNF
Second Choice
Green

Second line oral triptan

 
   
Zolmitriptan
(nasal spray)
View adult BNF View SPC online View childrens BNF
Second Choice
Green

Useful if patients vomit

 
   
04.07.04.02  Prophylaxis of migraine
Amitriptyline
(tablet/liquid)
View adult BNF View SPC online View childrens BNF
Formulary
Green

Off label use

 
   
Botulinum Toxin Type A
(injection)
View adult BNF View SPC online View childrens BNF
Formulary
Red
High Cost Medicine

Specify brand

 
Link  DPC Agreed Indications Botulinum Toxin (September 2013)
Link  NICE TA260: Botulinum toxin type A for the prevention of headaches in adults with chronic migraine
   
Pizotifen
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Green
 
   
Propranolol
(tablet/liquid)
View adult BNF View SPC online View childrens BNF
Formulary
Green
 
   
Topiramate (migraine prophylaxis)
(tablet/sprinkle capsule)
View adult BNF View SPC online View childrens BNF
Formulary
Green
 
   
04.08  Antiepileptics to top
04.08.01  Control of epilepsy
04.08.01  Carbamazepine and Oxcarbazepine
Carbamazepine
(tablet/MR tablet/liquid/suppositories)
View adult BNF View SPC online View childrens BNF
Formulary
Green

For partial seizures and secondary generalised tonic-clonic seizures

 
   
Eslicarbazepine (Zebinix®)
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended
 
   
Oxcarbazepine
(tablet/liquid)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended
 
   
04.08.01  Ethosuximide
Ethosuximide
(capsule/liquid)
View adult BNF View SPC online View childrens BNF
Formulary
Green
 
   
04.08.01  Gabapentin and pregabalin
Controlled Drug Gabapentin
(capsule)
View adult BNF View SPC online View childrens BNF
Formulary
Green
 
   
Controlled Drug Pregabalin
(capsule)
View adult BNF View SPC online View childrens BNF
Formulary

Amber Recommended Amber for epilepsy (not a first line choice)

Green Green for generalised anxiety disorder

Also green for neuropathic pain (see section 4.7.3)                                                      

 

 
   
04.08.01  Lacosamide to top
Lacosamide  (Vimpat ® )
(tablet/liquid/injection)
View adult BNF View SPC online View childrens BNF
Formulary

For refractory partial epilepsy

Amber Tablet/liquid

Red Injection is red on formulary for those NBM

 
   
04.08.01  Lamotrigine
Lamotrigine
(tablet/dispersible tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Green

For primary generalised epilepsy (including absences and myoclonus), partial seizures, secondary generalised tonic-clonic seizures.

 
   
04.08.01  Levetiracetam
Levetiracetam
(tablet/liquid)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended
 
   
Levetiracetam
(injection)
View adult BNF View SPC online View childrens BNF
Formulary
Red
 
   
04.08.01  Perampanel
Perampanel (Fycompa®)
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Initiation

Restricted Item  Treatment initiated and patients stabilised by neurology specialists

 
   
04.08.01  Phenobarbital and other barbiturates
Controlled Drug Phenobarbital
(tablet/liquid/injection)
View adult BNF View SPC online View childrens BNF
Formulary
Red

Restricted Item Child Health and existing patients only

 
   
Controlled Drug Phenobarbital elixir
(liquid)
View adult BNF View childrens BNF
Formulary
Red

unlicensed unlicensed

Restricted Item Specialist use only

 
   
Primidone
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Green

Existing patients only

 
   
04.08.01  Phenytoin to top
Phenytoin
(tablet/capsule/liquid/injection)
View adult BNF View SPC online View childrens BNF
Formulary
Green

Preparations containing phenytoin sodium are not bioequivalent to those containing phenytoin base. 

 
   
04.08.01  Rufinamide
Rufinamide (Inovelon®)
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Initiation

Restricted Item Initiated by Paediatric Neurologists for Lennox Gastaut syndrome

 
   
04.08.01  Tiagabine
Tiagabine (Gabitril®)
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended
 
   
04.08.01  Topiramate
Topiramate (epilepsy)
(tablet/sprinkle capsule)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended
 
   
04.08.01  Valproate
Sodium ValproateBlack Triangle
(tablet/MR tablet/liquid/injection)
View adult BNF View SPC online View childrens BNF
Formulary
Green

For primary generalised epilepsy (including absences and myoclonus), partial seizures, secondary generalised tonic-clonic seizures

 
Link  MHRA Drug Safety Update May 2018: Valproate medicines: Pregnancy Prevention Programme materials online
   
04.08.01  Vigabatrin to top
Vigabatrin (Sabril®)
(tablet/sachet)
View adult BNF View SPC online View childrens BNF
Formulary
Green
 
   
04.08.01  Zonisamide
Zonisamide (Zonegran®)
(capsule)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended
 
   
04.08.01  Benzodiazepines
Clobazam
(tablet/liquid)
View adult BNF View SPC online View childrens BNF
Formulary
Green
 
   
Clonazepam
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Green
 
   
04.08.01  Other Drugs
Brivaracetam (Briviact®)
(tablet/liquid/injection)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Initiation

Restricted Item For specialist initiation. Use restricted to selected patients. (e.g. inadequate seizure control or where other antiepileptic drugs are contraindicated, not tolerated or inappropriate)

 
   
Controlled Drug Cannabidiol (Epidyolex®)
(oral solution)
View adult BNF View SPC online View childrens BNF
Formulary
Red
NHS England

Restricted Item Registered specialist only. See NICE NG144 (section 1.5) for details on who should prescribe.

 
Link  NICE NG144: Cannabis-based medicinal products
Link  NICE TA614: Cannabidiol with clobazam for treating seizures associated with Dravet syndrome
Link  NICE TA615: Cannabidiol with clobazam for treating seizures associated with Lennox–Gastaut syndrome
   
Stiripentol (Diacomit®)
(capsule/sachet)
View adult BNF View SPC online View childrens BNF
Formulary

Restricted Item Specialist initiation only.

Amber Initiation Amber Initiation - for the treatment of severe myoclonic epilepsy.

Amber SCG Amber Shared Care Guidelines - for Dravet syndrome in children aged 3 years or older, adolescents and adults, in accordance with NICE guidelines CG137.

 
Link  DPC Shared Care Guideline for Stiripentol Feb 2020
Link  NICE CG137: Epilepsies: diagnosis and management Jan 2012
   
04.08.02  Drugs used in status epilepticus
Clonazepam
(injection)
View adult BNF View childrens BNF
Formulary
Green

unlicensed unlicensed

 
   
Diazepam (epilepsy)
(rectal liquid/injection/emulsion injection)
View adult BNF View SPC online View childrens BNF
Formulary
Green
 
   
Lorazepam (epilepsy)
(injection)
View adult BNF View SPC online View childrens BNF
Formulary
Green
 
   
Controlled Drug Midazolam buccal liquid (seizures)
View adult BNF View childrens BNF
Formulary
Amber Initiation

unlicensed unlicensed

Child Health only

 
   
Controlled Drug Midazolam oromucosal solution (seizures)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended

Amber for children with a seizure disorder

 
   
Paraldehyde and olive oil enema
View adult BNF View childrens BNF
Formulary
Red

unlicensed unlicensed

 
   
Controlled Drug Phenobarbital
(injection)
View adult BNF View SPC online View childrens BNF
Formulary
Red
 
   
Phenytoin
(injection)
View adult BNF View SPC online View childrens BNF
Formulary
Red
 
   
Pyridoxine
(injection)
View adult BNF View childrens BNF
Formulary
Red

unlicensed unlicensed

Restricted Item Child Health only.

 
   
04.08.03  Febrile convulsions to top
04.09  Drugs used in parkinsonism and related disorders
04.09.01  Dopaminergic drugs used in Parkinsons disease
04.09.01  Dopamine receptor agonists
Apomorphine
(injection)
View adult BNF View SPC online View childrens BNF
Formulary
Red
High Cost Medicine

Consultant initiated in severe disease

 
   
Bromocriptine
(tablet/capsule)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended

Not a first line option in Parkinson’s disease

 
   
Cabergoline
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended

Not a first line option in Parkinson’s disease

 
   
Pergolide
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Blue
 
   
Pramipexole
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended

Check base/salt equivalence

 
   
Ropinirole
(tablet/modified release tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended

An initial choice, particularly in younger patients.

 
   
Rotigotine
(patch)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended

Initiated/recommended by specialists only.

A replacement for oral dopamine agonists in patients with inadequate control of nocturnal/early morning symptoms.

In patients with inadequate compliance of complex regimens (cognitive problems, unable to swallow oral medication, motor problems).

As sole treatment in emergency situations when patients are unable to swallow oral drugs

 
   
04.09.01  Levodopa
Co-Beneldopa
(capsule/dispersible tablet/MR capsule)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended
 
   
Co-Careldopa
(tablet/MR tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended
 
   
Co-Careldopa with Entacapone
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended
 
   
Co-Careldopa (Duodopa®)
(gel cassette)
View adult BNF View SPC online View childrens BNF
Formulary
Red Specialist Centre
High Cost Medicine

Restricted Item For use as per specialist commissioning criteria set by NHS England

 
   
04.09.01  Monoamine-oxidase-B inhibitors to top
Rasagiline
(tablet)
View adult BNF View SPC online View childrens BNF
First Choice
Amber Recommended

First choice MAO-B inhibitor

 
Selegiline Hydrochloride
(tablet/liquid)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended
 
   
Safinamide
(tablets)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber Initiation

Restricted Item Restricted to use in late-stage Parkinson’s Disease and motor fluctuations where treatment with rasagiline/selegiline and entacapone has failed/not tolerated

 
Link  As per Shared Care Guidelines (Pending publication)
   
04.09.01  Catachol-O-methyltransferase inhibitors
Entacapone
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended

Can be used with levodopa preparations to reduce “off-time” in later Parkinson’s disease

 
   
Opicapone (Ongentys®)
(capsule)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended
 
   
Tolcapone (Tasmar®)
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Initiation

Restricted Item Specialist initiation.

Only when entacapone or opicapone are inappropriate

 
   
04.09.01  Amantadine
Amantadine
(capsule)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended
 
   
04.09.02  Antimuscarinic drugs used in parkinsonism
Orphenadrine
(tablet/liquid)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended
 
   
Procyclidine
(tablet/liquid/injection)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended
 
   
Trihexyphenidyl
(tablet/liquid)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended
 
   
04.09.03  Drugs used in essential tremor, chorea, tics, and related disorders
Haloperidol
(tablet/liquid/injection)
View adult BNF View SPC online View childrens BNF
Formulary
Green
 
   
Piracetam (Nootropil®)
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Initiation

Restricted Item Specialist initiation only

For the treatment of severe myoclonic epilepsy

 
   
Tetrabenazine
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Green
 
   
Riluzole (Rilutek®)
(tablet/liquid)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended
High Cost Medicine
 
Link  NICE TA20: Motor neurone disease - riluzole
   
04.09.03  Torsion dystonias and other involuntary movements to top
Botulinum Toxin Type A
(injection)
View adult BNF View SPC online View childrens BNF
Formulary
Red
High Cost Medicine

Specify brand and indication

Restricted Item Restricted use - discuss with directorate pharmacist

 
Link  DPC Agreed Indications Botulinum Toxin (September 2013)
   
04.09.04  Restless leg syndrome
Pramipexole
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Initiation

Specialist use only 

Third/fourth line for restless legs syndrome

 
   
04.10  Drugs used in substance dependence
04.10.01  Alcohol dependence
Acamprosate (Campral EC®)
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Initiation
 
   
Chlordiazepoxide
(capsule)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Initiation

For alcohol withdrawl

UHS users see local guideline

 
   
Disulfiram (Antabuse®)
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Initiation
 
   
Nalmefene
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Initiation

Only in conjunction with continuous psychosocial support.

 
Link  NICE TA325: Nalmefene for reducing alcohol consumption in people with alcohol dependence
   
Naltrexone (Adepend®)
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Initiation

Recommended by alcohol detoxification service.

 
   
Oxazepam
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Initiation

Off label use

UHS users see local guidelines

 
   
04.10.02  Nicotine dependence
Bupropion Hydrochloride (Zyban®)
(tablets)
View adult BNF View SPC online View childrens BNF
Formulary
Blue

As part of a smoking cessation programme.

 
   
Nicotine Replacement Therapy
View adult BNF View SPC online View childrens BNF
Formulary
Green

Formulary options - Nicotine patch [Nicorette Invisi patches]/Nicorette icy white gum/Nicorette inhalator/Nicorette Quickmist mouthspray.

As part of a smoking cessation programme.

 
   
Varenicline (Champix®)
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Green

As part of a smoking cessation programme.

 
Link  NICE TA123: Varenicline
   
04.10.03  Opioid dependence to top
04.10.03  Opioid substitution therapy
Controlled Drug Buprenorphine
(sublingual tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Initiation

Not initiated in UHS

 
Link  NICE TA114: Methadone and buprenorphine for the management of opioid dependence
   
Controlled Drug Buprenorphine (Espranor®)
(oral lyophilisate tablets)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Initiation

Not initiated in UHS

Red Triangle Espranor is not interchangeable with other buprenorphine products.

 
Link  NICE TA114: Methadone and buprenorphine for the management of opioid dependence
   
Controlled Drug Buprenorphine and Naloxone (Suboxone®)
(sublingual tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended

Not initiated in UHS

 
   
Controlled Drug Methadone 1mg/ml
(oral solution)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended

For management of opioid dependence only.

 
Link  NICE TA114: Methadone and buprenorphine for the management of opioid dependence
   
04.10.03  Adjunctive therapy and symptomatic treatment
04.10.03  Opioid-receptor antagonists
Naltrexone (Nalorex®)
(tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended
 
Link  NICE TA115: Naltrexone for the management of opioid dependence
   
04.11  Drugs for dementia
Donepezil
(tablet/orodispersible tablet)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended

Orodispersible  tablets only for patients unable to swallow tablets

 
Link  NICE TA217: Alzheimers disease donepezil, galantamine, rivastigmine and memantine
   
Galantamine
(tablet/MR capsule/liquid)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended

Liquid only for patients unable to swallow tablets

 
Link  NICE TA217: Alzheimers disease donepezil, galantamine, rivastigmine and memantine
   
Memantine
(tablet/liquid)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended

Southern Health - specialist initiated

Liquid only for patients unable to swallow tablets

 
Link  NICE TA217: Alzheimers disease donepezil, galantamine, rivastigmine and memantine
   
Rivastigmine
(capsule/liquid/patch)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Recommended

Liquid only for patients unable to swallow capsules

Also for dopaminergic drug-induced psychosis as 'Off-label use'

 
Link  NICE TA217: Alzheimers disease donepezil, galantamine, rivastigmine and memantine
   
04.12  Miscellaneous to top
Pirenzepine
(tablet)
View adult BNF View childrens BNF
Formulary
Red

Restricted ItemSpecialist use at Southern Health only.

unlicensed unlicensed

 
   
 ....
 Non Formulary Items
Alprazolam

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Amobarbital (amylobarbitone) and secobarbital (quinalbarbitone)  (Tuinal®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Amobarbital (amylobrbitone)  (Sodium Amytal®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Asenapine
(Sycrest)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Benzatropine

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Botulinum toxin type B  (NeuroBloc®)

View adult BNF View SPC online View childrens BNF
Non Formulary

Restricted Item May be used in exceptional circumstances if botulinum toxin type A not suitable. Discuss with directorate pharmacist.

Link  DPC Agreed Indications Botulinum Toxin (September 2013)
 
Buprenorphine  (Espranor®)
(Oral lyophilisate)

View adult BNF View SPC online View childrens BNF
Non Formulary
Black

Not initiated in UHS

Not evaluated by DPC

NOT EQUIVALENT TO OHER BUPRENORPHINE FORMULATIONS

See SPS summary here

 
Buprenorphine  (Hapoctasin)
(patch)

View adult BNF View SPC online View childrens BNF
Non Formulary

72 hour patch non-formulary as all other formulations are 96 hourly

 
Controlled Drug  Butobarbital (butobarbitone)  (Soneryl®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Cariprazine  (Reagila)
(capsules)

View adult BNF View SPC online View childrens BNF
Non Formulary
Black

Not supported by DPC

 
Dolasetron Mesilate  (Anzemet®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Dosulepin
(capsules/tablets)

View adult BNF View SPC online View childrens BNF
Non Formulary
Black

Red Triangle Not recommended nationally due to significant safety concerns (see NICE CG90)

 
Doxylamine and pyridoxine  (Xonvea®)
(tabs)

View adult BNF View SPC online View childrens BNF
Non Formulary
Black

DPC do not support use locally (Feb 2019).

Not supported by SMC (May 2019) or AWMSG (June 2019).

Link  NICE Evidence Summary Doxylamine/pyridoxine (Xonvea) for treating nausea and vomiting of pregnancy June 2019
 
Eletriptan  (Relpax®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Fentanyl  (Effentora® buccal tablets)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Flunarizine
(tabs/caps)

Non Formulary

unlicensed unlicensed

Link  NICE ESUOM33: Migraine prophylaxis: flunarizine Sept 2014
 
Flurazepam  (Dalmane®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Fluvoxamine
(tablets)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Fosaprepitant  (Ivemend®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Frovatriptan

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Hydromorphone  (Palladone®)
(capsule/MR capsule/injection)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Isocarboxazid

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Lisuride

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Lofexidine  (BritLofex®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Loprazolam

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Lurasidone  (Latuda®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Melatonin
(MR tablets/tablets/capsules/liquid)

View adult BNF View SPC online View childrens BNF
Non Formulary
Black

Use of melatonin is non-formulary in adults and in all indications in children other than sleep disorders as detailed in DPC Shared Care Guidance.

 

Due to lack of evidence for efficacy, safety and cost effectiveness melatonin treatment is not recommended for treatment of insomnia in adults (DPC Oct 2008) and for treatment of sleep disorders in patients with dementia/Alzheimers (DPC Aug 2017).

 
Methysergide  (Deseril®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Mianserin

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Naltrexone/ bupropion  (Mysimba®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Naratriptan  (Naramig®)

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Non Formulary
 
Nefopam

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Non Formulary
 
Nortriptyline
(tablets)

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Non Formulary
Black

Red Triangle Not recommended for use locally.

Consider alternatives according to indication.

For neuropathic pain refer to NICE CG173

For depression refer to NICE CG90

For insomnia refer to NICE CKS

 
Olanzapine pamoate  (ZypAdhera®)
(depot injection)

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Non Formulary
 
Controlled Drug  Oxycodone/Naloxone  (Targinact®)
(prolonged-release tablets)

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Non Formulary
Black

Not supported for prescribing locally. Included in NHS England guidance "Items which should not be routinely prescribed in primary care".

 

 
Paliperidone
(tablet)

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Non Formulary
 
Palonosetron  (Aloxi®)

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Non Formulary
 
Paracetamol and dextropropoxyphene  (Co-proxamol)

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Non Formulary

unlicensed unlicensed

 
Perphenazine

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Non Formulary
 
Rimonabant  (Acomplia®)

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Non Formulary
 
Rizatriptan  (Maxalt®)

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Non Formulary
 
Controlled Drug  Secobarbital (quinalbarbitone)  (Seconal Sodium® )

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Non Formulary
 
Sertindole  (Serdolect®)

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Non Formulary
 
Sibutramine Hydrochloride  (Reductil®)

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Non Formulary
 
Tasimelteon  (Hetlioz®)

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Non Formulary
 
Tolfenamic Acid  (Clotam®)

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Non Formulary
 
Tranylcypromine

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Non Formulary
 
Trimipramine
(tablets/capsules)

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Non Formulary
Black

Red Triangle Not recommended for use nationally.

Consider alternatives according to indication.

For neuropathic pain refer to NICE CG173

For depression refer to NICE CG90

For insomnia refer to NICE CKS

 
Tropisetron  (Navoban®)

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Non Formulary
 
Trytophan  (Optimax®)

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Non Formulary
 
Valproate semisodium Black Triangle 

View adult BNF View SPC online View childrens BNF
Non Formulary

e.g. Depakote<sup>®</sup>

Link  MHRA Drug Safety Update May 2018: Valproate medicines: Pregnancy Prevention Programme materials online
 
Valproic acid  (Convulex®)

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Non Formulary
 
Zaleplon  (Sonata®)

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Non Formulary
Link  NICE TA77: Guidance on the use of zaleplon, zolpidem and zopiclone for the short-term management of insomnia
 
Ziprasidone  (Zeldox®)

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Non Formulary
 
Zolpidem

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Non Formulary
Link  NICE TA77: Guidance on the use of zaleplon, zolpidem and zopiclone for the short-term management of insomnia
 
Zotepine  (Zoleptil®)

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine

Traffic Light Status Information

Status Description

Green

Suitable for prescribing by all in both primary and secondary care.  

Amber Recommended

Specialist recommended but suitable for continuation in primary care.  

Amber Initiation

Specialist initiated but suitable for continuation in primary care.  

Amber SCG

Specialist initiated and for continuation in primary care under a locally approved shared care guideline.  

Red

Suitable for prescribing in specialist settings (secondary care) only.   

Red Specialist Centre

Secondary care medicines to be used under specialised commissioning arrangements only.  

Blue

For primary care, either via FP10 or supplied through specialist services. These products may be stocked by hospital pharmacies only for supply to primary care units/wards or for continuing supplies for patients admitted on therapy.  

Black

Not recommended for use.  

netFormulary