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Southampton Joint Formulary
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 Formulary Chapter 4: Central nervous system - Full Chapter
04.02  Expand sub section  Drugs used in psychoses and related disorders
04.02.01  Expand sub section  Antipsychotic Drugs
04.02.01  Expand sub section  First-Generation Antipsychotic Drugs
Benperidol (Anquil)
(tablet)
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Formulary
Red

Restricted Item Southern Health use only

 
   
Chlorpromazine
(tablet/liquid)
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Formulary
Green
 
   
Flupentixol
(tablet)
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Formulary
Green
 
   
Haloperidol
(tablet/liquid/injection)
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Formulary
Green
 
   
Levomepromazine
(tablet/injection)
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Formulary
Green
 
   
Promazine Hydrochloride
(tablet/liquid/injection)
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Formulary
Green

Injection is unlicensed unlicensed 

 
   
Sulpiride
(tablet)
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Formulary
Green
 
   
Sulpiride
(liquid)
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Formulary
Red
 
   
Trifluoperazine
(tablet/liquid)
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Formulary
Green
 
   
Zuclopenthixol acetate (Clopixol Acuphase)
(injection)
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Formulary
Green
 
   
04.02.01  Expand sub section  Second-Generation Antipsychotic Drugs
Amisulpride
(tablet/liquid)
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Formulary
Green
 
   
Aripiprazole
(tablet)
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Amber Recommended
 
Link  NICE TA213: Aripiprazole for the treatment of schizophrenia in people aged 15 -17 years
Link  NICE TA292: Bipolar disorder (children) - aripiprazole
   
Clozapine
(tablet)
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Red

Restricted Item Specialist use only for treatment resistant schizophrenia

 
   
Olanzapine
(tablet/orodispersible tablet)
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Formulary
Green

Orodispersible tablets restricted to patients with swallowing difficulties

 
   
Quetiapine
(tablet)
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Formulary
Green
 
   
Risperidone
(tablet/liquid/orodispersible tablet)
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Formulary
Green

Orodispersible tablets restricted to patients with swallowing difficulties

 
   
04.02.02  Expand sub section  Antipsychotic depot injections to top
Aripiprazole (Abilify Maintena)
(depot injection)
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Formulary
Red

Restricted Item Secondary psychiatric care only

note For intramuscular injection

 
   
Flupentixol decanoate
(depot injection)
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Formulary
Amber Initiation

note For deep intramuscular injection

 
   
Fluphenazine decanoate (Modecate)
(depot injection)
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Formulary
Amber Initiation

note For deep intramuscular injection

 Product has been discontinued in UK, supplies expire in Aug 2020

 
   
Haloperidol decanoate (HALDOL Decanoate)
(depot injection)
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Formulary
Amber Initiation

note For deep intramuscular injection

 
   
Paliperidone palmitate (Xeplion / Trevicta)
(depot injection)
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Formulary
Red

Restricted Item  Specialist use at Southern Health/Solent NHS Trust

note For intramuscular injection. Xeplion = 1-monthly, Trevicta = 3-monthly maintenance dosing.

 
   
Pipotiazine palmitate (Piportil Depot)
(depot injection)
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Formulary
Amber Initiation

Restricted Item  Southern Health only

note For deep intramuscular injection

 
   
Risperidone (Risperdal Consta)
(depot injection)
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Formulary
Red

Restricted Item  Psychiatry only

note For deep intramuscular injection

 
   
Zuclopenthixol decanoate (Clopixol)
(depot injection)
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Formulary
Amber Initiation

note For deep intramuscular injection

 
   
04.02.03  Expand sub section  Drugs used for mania and hypomania
04.02.03  Expand sub section  Valproic acid
Sodium valproateBlack Triangle
(tablet/MR tablet/liquid)
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Formulary
Green

unlicensed Agreed locally for ‘off-label’ use in treatment of manic episodes in bipolar disorder instead of valproate semisodium.

Brand prescribing is not necessary for this indication.

 

 

 

 
Link  MHRA Drug Safety Update May 2018: Valproate medicines: Pregnancy Prevention Programme materials online
   
04.02.03  Expand sub section  Lithium
Lithium Carbonate
(MR tablet)
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Formulary
Amber Initiation

SPECIFY BRAND

 
   
Lithium Citrate
(liquid)
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Formulary
Amber Initiation

Not dose-equivalent to MR tablets

SPECIFY BRAND

 
   
 ....
 Non Formulary Items
Asenapine
(Sycrest)

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Non Formulary
 
Cariprazine  (Reagila)
(capsules)

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Non Formulary
Black

Not supported by DPC

 
Flunarizine
(tabs/caps)

Non Formulary

unlicensed unlicensed

Link  NICE ESUOM33: Migraine prophylaxis: flunarizine Sept 2014
 
Lurasidone  (Latuda)

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Non Formulary
 
Methysergide  (Deseril)

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Non Formulary
 
Olanzapine pamoate  (ZypAdhera)
(depot injection)

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Non Formulary
 
Paliperidone
(tablet)

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Non Formulary
 
Sertindole  (Serdolect)

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Non Formulary
 
Valproate semisodium Black Triangle 

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Non Formulary

e.g. Depakote<sup>®</sup>

Link  MHRA Drug Safety Update May 2018: Valproate medicines: Pregnancy Prevention Programme materials online
 
Ziprasidone  (Zeldox)

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Non Formulary
 
Zotepine  (Zoleptil®)

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine

Traffic Light Status Information

Status Description

Green

Suitable for prescribing by all in both primary and secondary care.  

Amber Recommended

Specialist recommended but suitable for continuation in primary care.  

Amber Initiation

Specialist initiated but suitable for continuation in primary care.  

Amber SCG

Specialist initiated and for continuation in primary care under a locally approved shared care guideline.  

Red

Suitable for prescribing in specialist settings (secondary care) only.   

Red Specialist Centre

Secondary care medicines to be used under specialised commissioning arrangements only.  

Blue

For primary care, either via FP10 or supplied through specialist services. These products may be stocked by hospital pharmacies only for supply to primary care units/wards or for continuing supplies for patients admitted on therapy.  

Black

Not recommended for use.  

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