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 Formulary Chapter 8: Malignant disease and immunosuppression - Full Chapter
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08.01.01  Expand sub section  Alkylating drugs
Bendamustine
(injection)
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Formulary
Red
High Cost Medicine
 
Link  NICE TA216: Bendamustine for the first-line treatment of chronic lymphocytic leukaemia
   
Cytotoxic Drug Busulfan
(tablet/injection)
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Formulary
Red

injection for BMT only

 
   
Cytotoxic Drug Carmustine
(injection/implants)
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Formulary
Red

unlicensed Injection is unlicensed

 
Link  NICE TA121: Carmustine implants and temozolomide for the treatment of newly diagnosed high-grade glioma
   
Cytotoxic Drug Chlorambucil
(tablet)
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Formulary
Amber Initiation
 
   
Cytotoxic Drug Cyclophosphamide
(tablet/injection)
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Formulary
Red
 
   
Cytotoxic Drug Ifosfamide
(injection)
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Formulary
Red
 
   
Cytotoxic Drug Lomustine
(capsule)
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Formulary
Red
 
   
Cytotoxic Drug Melphalan
(tablet)
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Formulary
Amber Initiation
 
   
Cytotoxic Drug Melphalan
(injection)
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Formulary
Red
 
   
Thiotepa
(infusion)
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Formulary
Red

For treatment of CNS diffuse large B cell lymphoma

 
   
Cytotoxic Drug Treosulfan (Trecondi)
(injection)
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Formulary
Red

Not appraised by NICE for use prior to alloHSCT in patients with non-malignant disease.

Note: Treosulfan (generic) is non-formulary for palliative treatment of epithelial ovarian cancer.

 
Link  NICE TA640: Treosulfan with fludarabine for malignant disease before allogenic stem cell transplant
   
 ....
 Non Formulary Items
Estramustine Phosphate  (Estracyt)

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Non Formulary
 
Cytotoxic Drug  Treosulfan
(injection/capsules)

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Non Formulary

Non-formulary for the palliative treatment of epithelial ovarian cancer 

 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine

Traffic Light Status Information

Status Description

Green

Suitable for prescribing by all in both primary and secondary care.  

Amber Recommended

Specialist recommended but suitable for continuation in primary care.  

Amber Initiation

Specialist initiated but suitable for continuation in primary care.  

Amber SCG

Specialist initiated and for continuation in primary care under a locally approved shared care guideline.  

Red

Suitable for prescribing in specialist settings (secondary care) only.   

Red Specialist Centre

Secondary care medicines to be used under specialised commissioning arrangements only.  

Blue

For primary care, either via FP10 or supplied through specialist services. These products may be stocked by hospital pharmacies only for supply to primary care units/wards or for continuing supplies for patients admitted on therapy.  

Black

Not recommended for use.  

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