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 Formulary Chapter 8: Malignant disease and immunosuppression - Full Chapter
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08.03.04.02  Expand sub section  Prostate cancer and gonadorelin analogues
 note 

See also section 6.7.2

The least costly Gonadotrophin-Releasing Hormone Analogue over the course of treatment and for the organisation administering it should be used for its licensed indications

08.03.04.02  Expand sub section  Gonadorelin analogues
08.03.04.02  Expand sub section  Anti-androgens
Abiraterone
(tablet)
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Red
High Cost Medicine
 
Link  NICE TA259: Abiraterone for castration-resistant metastatic prostate cancer previously treated with a docetaxel-containing regimen
Link  NICE TA387: Abiraterone for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicated
   
Bicalutamide
(tablet)
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Amber Recommended
 
   
Cyproterone acetate
(tablet)
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Amber Recommended
 
   
Enzalutamide (Xtandi)
(capsule)
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Red
High Cost Medicine

Note: not recommended for treating high-risk hormone-relapsed non-metastatic prostate cancer in adults, in accordance with NICE TA580

 
Link  NICE TA316: Enzalutamide for metastatic hormone‑relapsed prostate cancer previously treated with a docetaxel‑containing regimen
Link  NICE TA377: Enzalutamide for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicated
   
Flutamide
(tablet)
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Amber Recommended
 
   
Goserelin
(3.6mg/10.8mg implant)
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Amber Recommended
 
   
Leuprorelin acetate
(3.75mg depot injection)
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Amber Recommended
 
   
Triptorelin acetate/pamoate
(3mg/11.25mg/22.5mg depot injection)
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Amber Recommended
 
   
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine

Traffic Light Status Information

Status Description

Green

Suitable for prescribing by all in both primary and secondary care.  

Amber Recommended

Specialist recommended but suitable for continuation in primary care.  

Amber Initiation

Specialist initiated but suitable for continuation in primary care.  

Amber SCG

Specialist initiated and for continuation in primary care under a locally approved shared care guideline.  

Red

Suitable for prescribing in specialist settings (secondary care) only.   

Red Specialist Centre

Secondary care medicines to be used under specialised commissioning arrangements only.  

Blue

For primary care, either via FP10 or supplied through specialist services. These products may be stocked by hospital pharmacies only for supply to primary care units/wards or for continuing supplies for patients admitted on therapy.  

Black

Not recommended for use.  

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